Decorin (DCN) Peptide
DCN
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN975627
Quick Overview for Decorin (DCN) Peptide (ABIN975627)
Target
Decorin (DCN)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DCN antibody (Catalog #: ARP48200_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Decorin (DCN)
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Background
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DCN is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. DCN and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome.The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome.
Alias Symbols: CSCD, DSPG2, PG40, PGII, PGS2, SLRR1B
Protein Interaction Partner: AHSG,C1QA,COL14A1,COL1A1,COL1A2,COL4A1,COL4A3,COL4A4,COL4A5,COL4A6,COL5A1,DPT,EGFR,ELN,FBN1,FLNA,FN1,MMP2,MMP3,MMP7,PLA2G2A,SFTPD,TGFB1,THBS1,TNF,WISP1,AHSG,C1QA,COL14A1,COL6A1,EGFR,ELN,FLNA,PLA2G2A,SFTPD,TGFB1,TGFB2,TNF
Protein Size: 359 -
Molecular Weight
- 36 kDa
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Gene ID
- 1634
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NCBI Accession
- NM_001920, NP_001911
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UniProt
- P07585
Target
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